Maintenance of deleterious mutations and recombination suppression near mating-type loci under selfing

نویسندگان

چکیده

A recommendation of: Emilie Tezenas, Tatiana Giraud, Amandine Veber, Sylvain Billiard The fate of recessive deleterious or overdominant mutations near mating-type loci under partial selfing https://doi.org/10.1101/2022.10.07.511119

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Efficient Purging of Deleterious Mutations in Plants with Haploid Selfing

In diploid organisms, selfing reduces the efficiency of selection in removing deleterious mutations from a population. This need not be the case for all organisms. Some plants, for example, undergo an extreme form of selfing known as intragametophytic selfing, which immediately exposes all recessive deleterious mutations in a parental genome to selective purging. Here, we ask how effectively de...

متن کامل

Fungal mating-type loci

Fungi form one of the most ubiquitous and successful kingdoms of life on Earth. There are more than 100,000 known species of fungi, divided into four phyla — ascomycetes, basidiomycetes, zygomycetes and chytrids — and these have populated a vast array of biological niches, including those that are pathogens of animals (including humans and insects), plants and even other microorganisms. The mor...

متن کامل

A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci.

A mutation has been identified that suppresses the mating and sporulation defects of all mutations in the mating-type loci of S. cerevisiae. This suppressor, sir1-1, restores mating ability to mat alpha 1 and mat alpha 2 mutants and restores sporulation ability to mat alpha 2 and mata1 mutants. MATa sir1-1 strains exhibit a polar budding pattern and have reduced sensitivity to alpha-factor, bot...

متن کامل

Deleterious mutations, variable epistatic interactions, and the evolution of recombination.

In this paper, we examine the conditions that allow increased recombination to evolve in the presence of recurrent deleterious mutation. We focus on a three-locus model first studied by Feldman et al. (1980), which follows the dynamics of a modifier locus that alters the recombination rate between two loci subject to deleterious mutation. Although Feldman et al. (1980) indicated that increased ...

متن کامل

Maintenance of genetic variability under the pressure of neutral and deleterious mutations in a finite population.

In order to assess the effect of deleterious mutations on various measures of genic variation, approximate formulas have been developed for the frequency spectrum, the mean number of alleles in a sample, and the mean homozygosity; in some particular cases, exact formulas have been obtained. The assumptions made are that two classes of mutations exist, neutral and deleterious, and that selection...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Peer community in evolutionary biology

سال: 2023

ISSN: ['2551-668X']

DOI: https://doi.org/10.24072/pci.evolbiol.100635